PDBe 1bg1

X-ray diffraction
2.25Å resolution

TRANSCRIPTION FACTOR STAT3B/DNA COMPLEX

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Signal transducer and activator of transcription 3 Chain: A
Molecule details ›
Chain: A
Length: 596 amino acids
Theoretical weight: 68.22 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P42227 (Residues: 127-715; Coverage: 77%)
  • Best match: P42227-2 (Residues: 127-722)
Gene names: Aprf, Stat3
Sequence domains:
Structure domains:
DNA (5'-D(*TP*GP*CP*AP*TP*TP*TP*CP*CP*CP*GP*TP*AP*AP*AP*TP*CP*T)-3') Chain: B
Molecule details ›
Chain: B
Length: 18 nucleotides
Theoretical weight: 5.44 KDa

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID2
Spacegroup: I41
Unit cell:
a: 174Å b: 174Å c: 79.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.246 0.246 0.301
Expression system: Escherichia coli BL21