PDBe 1bd3

X-ray diffraction
1.93Å resolution

STRUCTURE OF THE APO URACIL PHOSPHORIBOSYLTRANSFERASE, 2 MUTANT C128V

Released:

Function and Biology Details

Reaction catalysed:
UMP + diphosphate = uracil + 5-phospho-alpha-D-ribose 1-diphosphate. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uracil phosphoribosyltransferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 243 amino acids
Theoretical weight: 27.56 KDa
Source organism: Toxoplasma gondii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q26998 (Residues: 2-244; Coverage: 100%)
Gene name: uprt
Sequence domains: Uracil phosphoribosyltransferase
Structure domains: Rossmann fold

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 60.6Å b: 141.69Å c: 71.37Å
α: 90° β: 115.13° γ: 90°
R-values:
R R work R free
0.186 0.186 not available
Expression system: Escherichia coli