› 1b5l

X-ray diffraction
2.1Å resolution

OVINE INTERFERON TAU

Released:
DOI: 10.2210/pdb1b5l/pdb
PDB entry 1b5l coloured by chain, front view.
PDB entry 1b5l coloured by chain, side view.
PDB entry 1b5l coloured by chain, top view.
Source organism: Komagataella pastoris
Primary publication:
Crystal structure of ovine interferon-tau at 2.1 A resolution.
Radhakrishnan R, Walter LJ, Subramaniam PS, Johnson HM, Walter MR
J Mol Biol 286 151-62 (1999)
PMID: 9931256

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157565 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon tau-1 Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 19.94 KDa
Source organism: Komagataella pastoris
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P56828 (Residues: 24-195; Coverage: 100%)
Gene names: IFNT1, OTP
Sequence domains: Interferon alpha/beta domain
Structure domains: Growth Hormone; Chain: A;

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 39.3Å b: 45.6Å c: 75.84Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.214 0.214 0.25
Expression system: Komagataella pastoris

Quick links

Citations

10 review citations

Interferons, interferon-like cytokines, and their receptors.
Pestka et al. (2004)
9 more

6 mentions without citation

A score of the ability of a three-dimensional protein model to retrieve its own sequence as a quantitative measure of its quality and appropriateness.
Martínez-Castilla et al. (2010)
5 more