PDBe 1b5d

X-ray diffraction
2.2Å resolution

DCMP Hydroxymethylase from T4 (Intact)

Released:

Function and Biology Details

Reaction catalysed:
5,10-methylenetetrahydrofolate + H(2)O + deoxycytidylate = tetrahydrofolate + 5-hydroxymethyldeoxycytidylate. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Deoxycytidylate 5-hydroxymethyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 246 amino acids
Theoretical weight: 28.52 KDa
Source organism: Enterobacteria phage T4
UniProt:
  • Canonical: P08773 (Residues: 1-246; Coverage: 100%)
Gene name: 42
Sequence domains: Thymidylate synthase
Structure domains: Thymidylate Synthase, chain A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2
Unit cell:
a: 176.23Å b: 53.29Å c: 75.86Å
α: 90° β: 115.54° γ: 90°
R-values:
R R work R free
0.16 0.16 0.208