PDBe 1b07

X-ray diffraction
2.5Å resolution

CRK SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Son of sevenless homolog 1 Chain: C
Molecule details ›
Chain: C
Length: 12 amino acids
Theoretical weight: 1.43 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: Q62245 (Residues: 1135-1144; Coverage: 1%)
Gene name: Sos1
Adapter molecule crk Chain: A
Molecule details ›
Chain: A
Length: 65 amino acids
Theoretical weight: 7.79 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q64010 (Residues: 134-190; Coverage: 19%)
Gene names: Crk, Crko
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: P43
Unit cell:
a: 36.8Å b: 36.8Å c: 52.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.242 0.242 0.354
Expression systems:
  • Not provided
  • Escherichia coli