PDBe 1axc

X-ray diffraction
2.6Å resolution

HUMAN PCNA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Proliferating cell nuclear antigen Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Structure domains: Proliferating Cell Nuclear Antigen
Cyclin-dependent kinase inhibitor 1 Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 22 amino acids
Theoretical weight: 2.78 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P38936 (Residues: 139-160; Coverage: 13%)
Gene names: CAP20, CDKN1, CDKN1A, CIP1, MDA6, PIC1, SDI1, WAF1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P3221
Unit cell:
a: 83.5Å b: 83.5Å c: 233.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.192 0.192 0.289