PDBe 1avq

X-ray diffraction
2.4Å resolution

TOROIDAL STRUCTURE OF LAMBDA EXONUCLEASE DETERMINED AT 2.4 ANGSTROMS

Released:
Source organism: Escherichia virus Lambda
Primary publication:
Toroidal structure of lambda-exonuclease.
Science 277 1824-7 (1997)
PMID: 9295273

Function and Biology Details

Reaction catalysed:
Exonucleolytic cleavage in the 5'- to 3'-direction to yield nucleoside 5'-phosphates. 
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exonuclease Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 228 amino acids
Theoretical weight: 26.17 KDa
Source organism: Escherichia virus Lambda
Expression system: Escherichia coli
UniProt:
  • Canonical: P03697 (Residues: 1-226; Coverage: 100%)
Gene names: exo, red-alpha, redX
Sequence domains: YqaJ-like viral recombinase domain
Structure domains: Lambda Exonuclease; Chain A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P41212
Unit cell:
a: 156.7Å b: 156.7Å c: 131.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.198 not available
Expression system: Escherichia coli