PDBe 1aut

X-ray diffraction
2.8Å resolution

Human activated protein C

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vitamin K-dependent protein C heavy chain Chain: C
Molecule details ›
Chain: C
Length: 250 amino acids
Theoretical weight: 28.09 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P04070 (Residues: 212-461; Coverage: 56%)
Gene name: PROC
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Vitamin K-dependent protein C light chain Chain: L
Molecule details ›
Chain: L
Length: 114 amino acids
Theoretical weight: 12.73 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P04070 (Residues: 84-197; Coverage: 26%)
Gene name: PROC
Sequence domains:
Structure domains: Laminin

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 57.06Å b: 89.6Å c: 101.23Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.184 not available