PDBe 1aqy

X-ray diffraction
1.75Å resolution


Source organism: Mus musculus
Primary publication:
Crystal structure of estrogen sulphotransferase.
Nat. Struct. Biol. 4 904-8 (1997)
PMID: 9360604

Function and Biology Details

Reaction catalysed:
3'-phosphoadenylyl sulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Estrogen sulfotransferase, testis isoform Chains: A, B
Molecule details ›
Chains: A, B
Length: 297 amino acids
Theoretical weight: 35.78 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P49891 (Residues: 1-295; Coverage: 100%)
Gene names: Ste, Sult1e1
Sequence domains: Sulfotransferase domain
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X9B
Spacegroup: P21212
Unit cell:
a: 96.44Å b: 79.18Å c: 80.55Å
α: 90° β: 90° γ: 90°
R R work R free
0.218 0.218 0.248
Expression system: Escherichia coli