PDBe 1aql

X-ray diffraction
2.8Å resolution

CRYSTAL STRUCTURE OF BOVINE BILE-SALT ACTIVATED LIPASE COMPLEXED WITH TAUROCHOLATE

Released:

Function and Biology Details

Reactions catalysed:
A steryl ester + H(2)O = a sterol + a fatty acid. 
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bile salt-activated lipase Chains: A, B
Molecule details ›
Chains: A, B
Length: 532 amino acids
Theoretical weight: 59.07 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P30122 (Residues: 19-550; Coverage: 92%)
Gene name: CEL
Sequence domains:
Structure domains: Rossmann fold

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SIEMENS
Spacegroup: P21212
Unit cell:
a: 130.23Å b: 104.09Å c: 120.18Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.275