› 1aq7

X-ray diffraction
2.2Å resolution

TRYPSIN WITH INHIBITOR AERUGINOSIN 98-B

Released:
DOI: 10.2210/pdb1aq7/pdb
PDB entry 1aq7 coloured by chain, front view.
PDB entry 1aq7 coloured by chain, side view.
PDB entry 1aq7 coloured by chain, top view.
Source organisms:
Primary publication:
Atomic Structure of the Trypsin-Aeruginosin 98-B Complex
Sandler B, Murakami M, Clardy J
J. Am. Chem. Soc. 120 595-596 (1998)

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133342 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine protease 1 Chain: A
Molecule details ›
Chain: A
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
AERUGINOSIN 98-B Chain: B
Molecule details ›
Chain: B
Length: 4 amino acids
Theoretical weight: 655 Da
Source organism: Microcystis aeruginosa NIES-98
Expression system: Not provided

Ligands and Environments

No bound ligands
2 modified residues:
Ligand DIL 1 x DIL
Ligand XPR 1 x XPR

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P61
Unit cell:
a: 48.3Å b: 48.3Å c: 145.2Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.164 0.237
Expression system: Not provided

Quick links

Citations

7 mentions without citation

Discrete-continuous duality of protein structure space.
Sadreyev et al. (2009)
6 more