PDBe 1aj0

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI DIHYDROPTEROATE SYNTHASE

Released:

Function and Biology Details

Reaction catalysed:
6-hydroxymethyl-7,8-dihydropterin diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydropteroate synthase Chain: A
Molecule details ›
Chain: A
Length: 282 amino acids
Theoretical weight: 30.65 KDa
Source organism: Escherichia coli
UniProt:
  • Canonical: P0AC13 (Residues: 1-282; Coverage: 100%)
Gene names: JW3144, b3177, dhpS, folP
Sequence domains: Pterin binding enzyme
Structure domains: Dihydropteroate (DHP) synthetase

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Unit cell:
a: 92.91Å b: 60.67Å c: 59.82Å
α: 90° β: 114.67° γ: 90°
R-values:
R R work R free
0.206 0.206 not available