PDBe 1a95

X-ray diffraction
2Å resolution

XPRTASE FROM E. COLI COMPLEXED WITH MG:CPRPP AND GUANINE

Released:

Function and Biology Details

Reaction catalysed:
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Xanthine phosphoribosyltransferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 152 amino acids
Theoretical weight: 16.99 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A9M5 (Residues: 1-152; Coverage: 100%)
Gene names: JW0228, b0238, gpp, gpt, gxu
Sequence domains: Phosphoribosyl transferase domain
Structure domains: Rossmann fold

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: P43212
Unit cell:
a: 94.2Å b: 94.2Å c: 165.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.207 0.232
Expression system: Escherichia coli