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SOLUTION NMR STRUCTURE OF TUMOR SUPPRESSOR P16INK4A, 18 STRUCTURES

Solution NMR
PDB entry 1a5e coloured by chain, ensemble of 18 models, front view.
PDB entry 1a5e coloured by chain, ensemble of 18 models, side view.
PDB entry 1a5e coloured by chain, ensemble of 18 models, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Cyclin-dependent kinase inhibitor 2A
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-154865

Macromolecules

Cyclin-dependent kinase inhibitor 2A
Chain: A
Length: 156 amino acids
Theoretical weight: 16.55 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P42771 (Residues: 1-156; Coverage: 100%)
Gene names: CDKN2, CDKN2A, MTS1
InterPro: Ankyrin repeat-containing domain superfamily
CATH: Ankyrin repeat-containing domain
SCOP: Ankyrin repeat
Cyclin-dependent kinase inhibitor 2A in PDB entry 1a5e, assembly 1, front view.
Cyclin-dependent kinase inhibitor 2A in PDB entry 1a5e, assembly 1, side view.
Cyclin-dependent kinase inhibitor 2A in PDB entry 1a5e, assembly 1, top view.
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