PDBe 1a4y

X-ray diffraction
2Å resolution

RIBONUCLEASE INHIBITOR-ANGIOGENIN COMPLEX

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Angiogenin Chains: B, E
Molecule details ›
Chains: B, E
Length: 123 amino acids
Theoretical weight: 14.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli str. K-12 substr. W3110
UniProt:
  • Canonical: P03950 (Residues: 25-147; Coverage: 100%)
Gene names: ANG, RNASE5
Sequence domains: Pancreatic ribonuclease
Structure domains: P-30 Protein
Ribonuclease inhibitor Chains: A, D
Molecule details ›
Chains: A, D
Length: 460 amino acids
Theoretical weight: 49.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli str. K-12 substr. W3110
UniProt:
  • Canonical: P13489 (Residues: 2-461; Coverage: 100%)
Gene names: PRI, RNH, RNH1
Sequence domains: Leucine Rich repeat
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 66.553Å b: 105.605Å c: 93.516Å
α: 90° β: 107.09° γ: 90°
R-values:
R R work R free
0.193 0.193 0.286
Expression system: Escherichia coli str. K-12 substr. W3110