PDBe 1a4q

X-ray diffraction
1.9Å resolution

Function and Biology Details

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuraminidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 390 amino acids
Theoretical weight: 43.43 KDa
Source organism: Influenza B virus (STRAIN B/BEIJING/1/87)
UniProt:
  • Canonical: P27907 (Residues: 76-465; Coverage: 84%)
Gene name: NA
Structure domains: Neuraminidase

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P3121
Unit cell:
a: 88.3Å b: 88.3Å c: 221.1Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.201 not available