PDBe 1a41

X-ray diffraction
2.3Å resolution

TYPE 1-TOPOISOMERASE CATALYTIC FRAGMENT FROM VACCINIA VIRUS

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA topoisomerase 1B Chain: A
Molecule details ›
Chain: A
Length: 234 amino acids
Theoretical weight: 27.27 KDa
Source organism: Vaccinia virus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P68698 (Residues: 81-314; Coverage: 75%)
Gene names: H6R, TOP1, VACWR104
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P41212
Unit cell:
a: 81.7Å b: 81.7Å c: 84.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.227 0.227 0.309
Expression system: Escherichia coli BL21