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TETRATRICOPEPTIDE REPEATS OF PROTEIN PHOSPHATASE 5

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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EC 3.1.3.16: Protein-serine/threonine phosphatase

Reaction catalysed:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Systematic name:
Phosphoprotein phosphohydrolase
Alternative Name(s):
  • 3-hydroxy 3-methylglutaryl coenzymeA reductase phosphatase
  • Aspergillus awamori acid protein phosphatase
  • BCKDH phosphatase
  • Branched-chain alpha-keto acid dehydrogenase phosphatase
  • Calcineurin
  • Casein phosphatase
  • HMG-CoA reductase phosphatase
  • Phosphatase 2A
  • Phosphatase 2B
  • Phosphatase C-II
  • Phosphatase H-II
  • Phosphatase I
  • Phosphatase IB
  • Phosphatase II
  • Phosphatase III
  • Phosphatase IV
  • Phosphatase SP
  • Phosphoprotein phosphatase
  • Phosphopyruvate dehydrogenase phosphatase
  • Phosphospectrin phosphatase
  • Polycation modulated (PCM-) phosphatase
  • Protein D phosphatase
  • Protein phosphatase
  • Protein phosphatase-1
  • Protein phosphatase-2A
  • Protein phosphatase-2B
  • Protein phosphatase-2C
  • Serine/threonine specific protein phosphatase

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF08321
Domain description: PPP5 TPR repeat region
Occurring in:
  1. Serine/threonine-protein phosphatase 5
The deposited structure of PDB entry 1a17 contains 1 copy of Pfam domain PF08321 (PPP5 TPR repeat region) in Serine/threonine-protein phosphatase 5. Showing 1 copy in chain A.

PF00515
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Serine/threonine-protein phosphatase 5
The deposited structure of PDB entry 1a17 contains 1 copy of Pfam domain PF00515 (Tetratricopeptide repeat) in Serine/threonine-protein phosphatase 5. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR019734
Domain description: Tetratricopeptide repeat
Occurring in:
  1. Serine/threonine-protein phosphatase 5
IPR011990
Domain description: Tetratricopeptide-like helical domain superfamily
Occurring in:
  1. Serine/threonine-protein phosphatase 5
IPR013235
Domain description: PPP domain
Occurring in:
  1. Serine/threonine-protein phosphatase 5

Structure domain

CATH CATH domain
1.25.40.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Homology: Tetratricopeptide repeat domain
Occurring in:
  1. Serine/threonine-protein phosphatase 5
The deposited structure of PDB entry 1a17 contains 1 copy of CATH domain 1.25.40.10 (Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat) in Serine/threonine-protein phosphatase 5. Showing 1 copy in chain A.
SCOP SCOP annotation
48453
Class: All alpha proteins
Fold: alpha-alpha superhelix
Superfamily: TPR-like
Occurring in:
  1. Serine/threonine-protein phosphatase 5
The deposited structure of PDB entry 1a17 contains 1 copy of SCOP domain 48453 (Tetratricopeptide repeat (TPR)) in Serine/threonine-protein phosphatase 5. Showing 1 copy in chain A.

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