PDBe 1ztb

X-ray diffraction
2.65Å resolution

Crystal Structure of Chorismate Synthase from Mycobacterium tuberculosis

Released:

Function and Biology Details

Reaction catalysed:
5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chorismate synthase Chain: A
Molecule details ›
Chain: A
Length: 401 amino acids
Theoretical weight: 41.84 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WPY1 (Residues: 1-401; Coverage: 100%)
Gene names: MTCY159.16, Rv2540c, aroC, aroF
Sequence domains: Chorismate synthase
Structure domains: Chorismate synthase AroC

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P6422
Unit cell:
a: 129.756Å b: 129.756Å c: 156.795Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.162 0.221
Expression system: Escherichia coli