PDBe 1zs8

X-ray diffraction
3Å resolution

Crystal Structure of the Murine MHC Class Ib Molecule M10.5

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero decamer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Major histocompatibility complex class Ib M10.5 Chains: A, C, E, G, I
Molecule details ›
Chains: A, C, E, G, I
Length: 274 amino acids
Theoretical weight: 31.42 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: NEW Q860W6 (Residues: 22-295; Coverage: 90%)
Gene name: H2-M10.4
Sequence domains: Immunoglobulin C1-set domain
Structure domains:
Beta-2-microglobulin Chains: B, D, F, H, J
Molecule details ›
Chains: B, D, F, H, J
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: NEW P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 12.3.1
Spacegroup: P212121
Unit cell:
a: 124.11Å b: 134.71Å c: 149.37Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.307 0.307 0.308
Expression system: Trichoplusia ni