PDBe 1zmm

X-ray diffraction
1.6Å resolution

Crystal structure of human alpha-defensin-4

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structures of human alpha-defensins HNP4, HD5, and HD6.
Protein Sci. 15 2749-60 (2006)
PMID: 17088326

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil defensin 4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 33 amino acids
Theoretical weight: 3.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P12838 (Residues: 64-96; Coverage: 42%)
Gene names: DEF4, DEFA4
Sequence domains: Mammalian defensin

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: C2
Unit cell:
a: 72.004Å b: 39.255Å c: 48.118Å
α: 90° β: 110.08° γ: 90°
R-values:
R R work R free
0.187 0.185 0.218
Expression system: Escherichia coli