PDBe 1zmk

X-ray diffraction
1.3Å resolution

Crystal structure of human alpha-defensin-2 (variant Gly16-> D-ALA), P 42 21 2 space group

Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo octamer
Entry contents:
1 distinct polypeptide molecule
Neutrophil defensin 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 29 amino acids
Theoretical weight: 3.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P59666 (Residues: 66-94; Coverage: 39%)
Gene names: DEF3, DEFA3
Sequence domains: Mammalian defensin

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P42212
Unit cell:
a: 47.148Å b: 47.148Å c: 50.643Å
α: 90° β: 90° γ: 90°
R R work R free
0.161 0.16 0.177
Expression system: Escherichia coli