PDBe 1z8u

X-ray diffraction
2.4Å resolution

Crystal structure of oxidized alpha hemoglobin bound to AHSP

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: B, D
Molecule details ›
Chains: B, D
Length: 142 amino acids
Theoretical weight: 15.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P69905 (Residues: 1-142; Coverage: 100%)
Gene names: HBA1, HBA2
Sequence domains: Globin
Structure domains: Globins
Alpha-hemoglobin-stabilizing protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 102 amino acids
Theoretical weight: 11.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9NZD4 (Residues: 1-102; Coverage: 100%)
Gene names: AHSP, EDRF, ERAF
Sequence domains: Alpha-haemoglobin stabilising protein
Structure domains: Alpha-hemoglobin stabilizing protein

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2
Unit cell:
a: 65.808Å b: 113.747Å c: 80.098Å
α: 90° β: 94.66° γ: 90°
R-values:
R R work R free
0.22 0.222 0.252
Expression system: Escherichia coli