PDBe 1yxr

Solution NMR

NMR Structure of VPS4A MIT Domain

Released:
Source organism: Homo sapiens
Entry authors: Scott JA, Gaspar J, Stuchell M, Alam S, Skalicky J, Sundquist WI

Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vacuolar protein sorting-associated protein 4A Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 9.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9UN37 (Residues: 1-77; Coverage: 18%)
Gene names: VPS4, VPS4A
Sequence domains: MIT (microtubule interacting and transport) domain
Structure domains: Hypothetical protein 1500032h18.

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: automated NOE assignment using CYANA and torsion angle dynamics for structure calculations
Chemical shifts: BMR6573  
Expression system: Escherichia coli BL21