PDBe 1yvp

X-ray diffraction
2.2Å resolution

Ro autoantigen complexed with RNAs

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
Macromolecules (3 distinct):
60 kDa SS-A/Ro ribonucleoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 538 amino acids
Theoretical weight: 60.77 KDa
Source organism: Xenopus laevis
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P42700 (Residues: 1-538; Coverage: 100%)
Gene name: trove2
Sequence domains: TROVE domain
Structure domains: Rossmann fold
Y RNA sequence, first strand Chains: C, E, G, H
Molecule details ›
Chains: C, E, G, H
Length: 10 nucleotides
Theoretical weight: 3.32 KDa
Source organism: Synthetic construct
Expression system: Not provided
Y RNA sequence, second strand Chains: D, F
Molecule details ›
Chains: D, F
Length: 10 nucleotides
Theoretical weight: 3.52 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P21
Unit cell:
a: 60.3Å b: 153.65Å c: 80.56Å
α: 90° β: 92.8° γ: 90°
R-values:
R R work R free
0.202 0.202 0.238
Expression systems:
  • Trichoplusia ni
  • Not provided