PDBe 1ydp

X-ray diffraction
1.9Å resolution

1.9A crystal structure of HLA-G

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, alpha chain G Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P17693 (Residues: 26-300; Coverage: 88%)
Gene names: HLA-6.0, HLA-G, HLAG
Sequence domains: Immunoglobulin C1-set domain
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Histone H2AX Chain: P
Molecule details ›
Chain: P
Length: 9 amino acids
Theoretical weight: 1.15 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P16104 (Residues: 78-86; Coverage: 6%)
Gene names: H2AFX, H2AX

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3221
Unit cell:
a: 77.15Å b: 77.15Å c: 151.72Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.235 0.264
Expression systems:
  • Escherichia coli BL21
  • Not provided