PDBe 1y6l

X-ray diffraction
1.85Å resolution

Human ubiquitin conjugating enzyme E2E2

Released:

Function and Biology Details

Reaction catalysed:
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ubiquitin-conjugating enzyme E2 E2 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 149 amino acids
Theoretical weight: 16.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96LR5 (Residues: 55-201; Coverage: 73%)
Gene names: UBCH8, UBE2E2
Sequence domains: Ubiquitin-conjugating enzyme
Structure domains: Ubiquitin Conjugating Enzyme

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: C2
Unit cell:
a: 108.109Å b: 36.11Å c: 130.568Å
α: 90° β: 99.92° γ: 90°
R-values:
R R work R free
0.194 0.192 0.246
Expression system: Escherichia coli