PDBe 1xz0

X-ray diffraction
2.8Å resolution

Crystal structure of CD1a in complex with a synthetic mycobactin lipopeptide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
T-cell surface glycoprotein CD1a Chains: A, C
Molecule details ›
Chains: A, C
Length: 279 amino acids
Theoretical weight: 31.9 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P06126 (Residues: 18-294; Coverage: 89%)
Gene name: CD1A
Sequence domains: Immunoglobulin C1-set domain
Structure domains:
Beta-2-microglobulin Chains: B, D
Molecule details ›
Chains: B, D
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21
Unit cell:
a: 55.961Å b: 43.235Å c: 209.944Å
α: 90° β: 91.04° γ: 90°
R-values:
R R work R free
0.218 0.217 0.277
Expression system: Drosophila melanogaster