PDBe 1x7q

X-ray diffraction
1.45Å resolution

Crystal structure of HLA-A*1101 with sars nucleocapsid peptide

Released:
Source organisms:
Primary publication:
High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide.
Acta Crystallogr. D Biol. Crystallogr. 61 1031-40 (2005)
PMID: 16041067

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A-11 alpha chain Chain: A
Molecule details ›
Chain: A
Length: 275 amino acids
Theoretical weight: 31.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13746 (Residues: 25-299; Coverage: 81%)
Gene names: HLA-A, HLAA
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Nucleoprotein Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 1.05 KDa
Source organism: SARS coronavirus
Expression system: Not provided
UniProt:
  • Canonical: P59595 (Residues: 362-370; Coverage: 2%)
Gene names: 9a, N

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21
Unit cell:
a: 58.465Å b: 80.623Å c: 56.57Å
α: 90° β: 116.79° γ: 90°
R-values:
R R work R free
0.135 0.132 0.181
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided