PDBe 1x6g

Solution NMR

Solution structures of the SH3 domain of human megakaryocyte-associated tyrosine-protein kinase.

Released:
Source organism: Homo sapiens
Entry authors: Sato M, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Megakaryocyte-associated tyrosine-protein kinase Chain: A
Molecule details ›
Chain: A
Length: 81 amino acids
Theoretical weight: 8.74 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P42679 (Residues: 41-108; Coverage: 13%)
Gene names: CTK, HYL, MATK
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: torsion angle dynamics
Chemical shifts: BMR10245  
Expression system: Not provided