PDBe 1wu9

X-ray diffraction
1.54Å resolution

Crystal structure of the C-terminal domain of the end-binding protein 1 (EB1)

Released:
Source organism: Homo sapiens
Primary publication:
Structural insights into the EB1-APC interaction.
EMBO J. 24 261-9 (2005)
PMID: 15616574

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated protein RP/EB family member 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 80 amino acids
Theoretical weight: 9.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15691 (Residues: 191-268; Coverage: 29%)
Gene name: MAPRE1
Sequence domains: EB1-like C-terminal motif

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: P21
Unit cell:
a: 32Å b: 37.3Å c: 56.5Å
α: 90° β: 105.4° γ: 90°
R-values:
R R work R free
0.183 0.181 0.22
Expression system: Escherichia coli BL21(DE3)