PDBe 1wh8

Solution NMR

Solution structure of the third CUT domain of human Homeobox protein Cux-2

Source organism: Homo sapiens
Entry authors: Nameki N, Tochio N, Koshiba S, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Homeobox protein cut-like 2 Chain: A
Molecule details ›
Chain: A
Length: 111 amino acids
Theoretical weight: 12.1 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: O14529 (Residues: 1028-1125; Coverage: 7%)
Gene names: CUTL2, CUX2, KIAA0293
Sequence domains: CUT domain
Structure domains: lambda repressor-like DNA-binding domains

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: torsion angle dynamics, restrained molecular dynamics
Chemical shifts: BMR10094  
Expression system: Not provided