PDBe 1war

X-ray diffraction
2.22Å resolution

Recombinant Human Purple Acid Phosphatase expressed in Pichia Pastoris

Released:

Function and Biology Details

Reaction catalysed:
A phosphate monoester + H(2)O = an alcohol + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tartrate-resistant acid phosphatase type 5 Chain: A
Molecule details ›
Chain: A
Length: 310 amino acids
Theoretical weight: 35.05 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
  • Canonical: P13686 (Residues: 19-325; Coverage: 100%)
Gene name: ACP5
Sequence domains: Calcineurin-like phosphoesterase
Structure domains: Purple Acid Phosphatase; chain A, domain 2

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P43212
Unit cell:
a: 80.538Å b: 80.538Å c: 99.998Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.141 0.138 0.198
Expression system: Komagataella pastoris