PDBe 1vfe

X-ray diffraction
2.3Å resolution

HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY SER (R121S)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lactotransferrin Chain: A
Molecule details ›
Chain: A
Length: 333 amino acids
Theoretical weight: 36.95 KDa
Source organism: Homo sapiens
Expression system: Cricetinae
UniProt:
  • Canonical: NEW P02788 (Residues: 20-352; Coverage: 48%)
Gene names: GIG12, LF, LTF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: C2
Unit cell:
a: 97.9Å b: 78.8Å c: 58.9Å
α: 90° β: 99.2° γ: 90°
R-values:
R R work R free
0.196 0.196 0.27
Expression system: Cricetinae