PDBe 1v18

X-ray diffraction
2.1Å resolution

The crystal structure of beta-catenin armadillo repeat complexed with a phosphorylated APC 20mer repeat.


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Catenin beta-1 Chain: A
Molecule details ›
Chain: A
Length: 538 amino acids
Theoretical weight: 58.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21
  • Canonical: Q02248 (Residues: 134-671; Coverage: 69%)
Gene names: Catnb, Ctnnb1
Sequence domains: Armadillo/beta-catenin-like repeat
Structure domains: Leucine-rich Repeat Variant
Adenomatous polyposis coli protein Chain: B
Molecule details ›
Chain: B
Length: 47 amino acids
Theoretical weight: 5.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
  • Canonical: P25054 (Residues: 1482-1528; Coverage: 2%)
Gene names: APC, DP2.5
Sequence domains: APC repeat

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.2
Spacegroup: P212121
Unit cell:
a: 50.83Å b: 90.06Å c: 122.81Å
α: 90° β: 90° γ: 90°
R R work R free
0.207 0.207 0.253
Expression system: Escherichia coli BL21