PDBe 1uou

X-ray diffraction
2.11Å resolution

Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Thymidine phosphorylase Chain: A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: C2
Unit cell:
a: 69.99Å b: 66.09Å c: 96.87Å
α: 90° β: 106.54° γ: 90°
R R work R free
0.192 0.188 0.258
Expression system: Escherichia coli