PDBe 1ucp

Solution NMR

NMR structure of the PYRIN domain of human ASC

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apoptosis-associated speck-like protein containing a CARD Chain: A
Molecule details ›
Chain: A
Length: 91 amino acids
Theoretical weight: 10.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9ULZ3 (Residues: 1-91; Coverage: 47%)
Gene names: ASC, CARD5, PYCARD, TMS1
Sequence domains: PAAD/DAPIN/Pyrin domain
Structure domains: Death Domain, Fas

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 47%
Refinement method: torsion angle dynamics
Chemical shifts: BMR5780  
Expression system: Escherichia coli