PDBe 1tz8

X-ray diffraction
1.85Å resolution

The monoclinic crystal structure of transthyretin in complex with diethylstilbestrol


Function and Biology Details

Structure analysis Details

Assemblies composition:
homo tetramer (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Transthyretin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 127 amino acids
Theoretical weight: 13.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P02766 (Residues: 21-147; Coverage: 100%)
Gene names: PALB, TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: C2
Unit cell:
a: 74.271Å b: 96.961Å c: 81.717Å
α: 90° β: 107.94° γ: 90°
R R work R free
0.198 0.195 0.221
Expression system: Escherichia coli