PDBe 1tr2

X-ray diffraction
2.9Å resolution

Crystal structure of human full-length vinculin (residues 1-1066)

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of human vinculin.
Structure 12 1189-97 (2004)
PMID: 15242595

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vinculin Chains: A, B
Molecule details ›
Chains: A, B
Length: 1066 amino acids
Theoretical weight: 118.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P18206 (Residues: 1-1134; Coverage: 94%)
  • Best match: P18206-2 (Residues: 1-1066)
Gene name: VCL
Sequence domains: Vinculin family
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 66.74Å b: 154.08Å c: 108.95Å
α: 90° β: 90.44° γ: 90°
R-values:
R R work R free
0.236 0.232 0.3
Expression system: Escherichia coli