PDBe 1tfh

X-ray diffraction
2.4Å resolution

EXTRACELLULAR DOMAIN OF HUMAN TISSUE FACTOR

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tissue factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 219 amino acids
Theoretical weight: 24.83 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P13726 (Residues: 33-251; Coverage: 83%)
Gene name: F3
Sequence domains: Interferon-alpha/beta receptor, fibronectin type III
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELLIOTT GX-18
Spacegroup: P212121
Unit cell:
a: 64.393Å b: 85.828Å c: 112.901Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.217 0.297
Expression system: Escherichia coli BL21(DE3)