PDBe 1taz

X-ray diffraction
1.77Å resolution

Catalytic Domain Of Human Phosphodiesterase 1B

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 41.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q01064 (Residues: 146-506; Coverage: 67%)
Gene names: PDE1B, PDE1B1, PDES1B
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P43212
Unit cell:
a: 87.232Å b: 87.232Å c: 134.151Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.182 0.193
Expression system: Escherichia coli