PDBe 1svc

X-ray diffraction
2.6Å resolution

NFKB P50 HOMODIMER BOUND TO DNA

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Nuclear factor NF-kappa-B p50 subunit Chain: P
Molecule details ›
Chain: P
Length: 365 amino acids
Theoretical weight: 41.13 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P19838 (Residues: 2-39, 40-365; Coverage: 38%)
  • Best match: P19838-3 (Residues: 10-185)
Gene name: NFKB1
Sequence domains:
Structure domains:
DNA (5'-D(*AP*GP*AP*TP*GP*GP*GP*GP*AP*AP*TP*CP*CP*CP*CP*TP*A P*GP*A)-3') Chain: D
Molecule details ›
Chain: D
Length: 19 nucleotides
Theoretical weight: 5.88 KDa

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P41212
Unit cell:
a: 137Å b: 137Å c: 57Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.225 0.225 0.286
Expression system: Not provided