PDBe 1suv

Electron Microscopy
7.5Å resolution

Structure of Human Transferrin Receptor-Transferrin Complex

Released:
Source organism: Homo sapiens
Primary publication:
Structure of the human transferrin receptor-transferrin complex.
Cell 116 565-76 (2004)
PMID: 14980223

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Transferrin receptor protein 1, serum form Chains: A, B
Molecule details ›
Chains: A, B
Length: 639 amino acids
Theoretical weight: 71.62 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P02786 (Residues: 122-760; Coverage: 84%)
Gene name: TFRC
Sequence domains:
Serotransferrin Chains: C, D
Molecule details ›
Chains: C, D
Length: 329 amino acids
Theoretical weight: 36.41 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: P02787 (Residues: 22-350; Coverage: 49%)
Gene names: PRO1400, TF
Sequence domains: Transferrin
Serotransferrin, C-lobe Chains: E, F
Molecule details ›
Chains: E, F
Length: 345 amino acids
Theoretical weight: 38.3 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 7.5Å
Expression system: Cricetulus griseus