PDBe 1sqm

X-ray diffraction
2.3Å resolution

STRUCTURE OF [R563A] LEUKOTRIENE A4 HYDROLASE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukotriene A-4 hydrolase Chain: A
Molecule details ›
Chain: A
Length: 610 amino acids
Theoretical weight: 69.15 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09960 (Residues: 2-611; Coverage: 100%)
Gene names: LTA4, LTA4H
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: P212121
Unit cell:
a: 78Å b: 86.85Å c: 98.95Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.19 0.23
Expression system: Escherichia coli