› 1ryo

X-ray diffraction
1.2Å resolution

Human serum transferrin, N-lobe bound with oxalate

Released:
DOI: 10.2210/pdb1ryo/pdb
PDB entry 1ryo coloured by chain, front view.
PDB entry 1ryo coloured by chain, side view.
PDB entry 1ryo coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The oxalate effect on release of iron from human serum transferrin explained.
Halbrooks PJ, Mason AB, Adams TE, Briggs SK, Everse SJ
J Mol Biol 339 217-26 (2004)
PMID: 15123433

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136222 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serotransferrin Chain: A
Molecule details ›
Chain: A
Length: 327 amino acids
Theoretical weight: 36.21 KDa
Source organism: Homo sapiens
Expression system: Mesocricetus auratus
UniProt:
  • Canonical: P02787 (Residues: 20-346; Coverage: 48%)
Gene names: PRO1400, TF
Sequence domains: Transferrin
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:
Ligand OXL 1 x OXL
Ligand FE 1 x FE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: P212121
Unit cell:
a: 44.092Å b: 57.252Å c: 135.988Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.221 0.221 0.235
Expression system: Mesocricetus auratus

Quick links

Citations

3 review citations

The long history of iron in the Universe and in health and disease.
Sheftel et al. (2012)
2 more

3 mentions without citation

Progress in super long loop prediction.
Zhao et al. (2011)
2 more