PDBe 1rke

X-ray diffraction
2.35Å resolution

Human vinculin head (1-258) in complex with human vinculin tail (879-1066)

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin Chain: A
Molecule details ›
Chain: A
Length: 262 amino acids
Theoretical weight: 29.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P18206 (Residues: 1-258; Coverage: 23%)
Gene name: VCL
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)
Vinculin Chain: B
Molecule details ›
Chain: B
Length: 185 amino acids
Theoretical weight: 20.84 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P18206 (Residues: 947-1134; Coverage: 16%)
  • Best match: P18206-2 (Residues: 882-1066)
Gene name: VCL
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P21212
Unit cell:
a: 86.603Å b: 161.648Å c: 36.04Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.278
Expression system: Escherichia coli