PDBe 1rkc

X-ray diffraction
2.7Å resolution

Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Talin-1 Chain: B
Molecule details ›
Chain: B
Length: 26 amino acids
Theoretical weight: 2.91 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P54939 (Residues: 1944-1969; Coverage: 1%)
Gene names: TLN, TLN1
Vinculin Chain: A
Molecule details ›
Chain: A
Length: 262 amino acids
Theoretical weight: 29.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P18206 (Residues: 1-258; Coverage: 23%)
Gene name: VCL
Structure domains: Four Helix Bundle (Hemerythrin (Met), subunit A)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: I4132
Unit cell:
a: 155.68Å b: 155.68Å c: 155.68Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.244 0.244 0.335
Expression system: Escherichia coli