PDBe 1r4c

X-ray diffraction
2.18Å resolution

N-Truncated Human Cystatin C; Dimeric Form With 3D Domain Swapping

Released:
Source organism: Homo sapiens
Primary publication:
Domain swapping in N-truncated human cystatin C.
J. Mol. Biol. 341 151-60 (2004)
PMID: 15312769

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo octamer
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cystatin-C Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 110 amino acids
Theoretical weight: 12.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01034 (Residues: 37-146; Coverage: 92%)
Gene name: CST3
Sequence domains: Cystatin domain
Structure domains: Nuclear Transport Factor 2; Chain: A,

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: MAX II BEAMLINE I711
Spacegroup: C2221
Unit cell:
a: 97.147Å b: 99.639Å c: 206.066Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.218 0.259
Expression system: Escherichia coli