› 1qqe

X-ray diffraction
2.9Å resolution

CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17

Released:
DOI: 10.2210/pdb1qqe/pdb
PDB entry 1qqe coloured by chain, front view.
PDB entry 1qqe coloured by chain, side view.
PDB entry 1qqe coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of the vesicular transport protein Sec17: implications for SNAP function in SNARE complex disassembly.
Rice LM, Brunger AT
Mol Cell 4 85-95 (1999)
PMID: 10445030

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152393 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-soluble NSF attachment protein Chain: A
Molecule details ›
Chain: A
Length: 292 amino acids
Theoretical weight: 32.82 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P32602 (Residues: 1-292; Coverage: 100%)
Gene names: SEC17, YBL0505, YBL050W, YBL0517
Sequence domains: Soluble NSF attachment protein, SNAP
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: P41
Unit cell:
a: 107.9Å b: 107.9Å c: 46.1Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.262 0.26 0.283
Expression system: Escherichia coli

Quick links

Citations

19 review citations

The mechanisms of vesicle budding and fusion.
Bonifacino et al. (2004)
18 more

20 mentions without citation

Mechanism of neurotransmitter release coming into focus.
Rizo J. (2018)
19 more