PDBe 1qgk

X-ray diffraction
2.5Å resolution

STRUCTURE OF IMPORTIN BETA BOUND TO THE IBB DOMAIN OF IMPORTIN ALPHA

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Importin subunit beta-1 Chain: A
Molecule details ›
Chain: A
Length: 876 amino acids
Theoretical weight: 97.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14974 (Residues: 1-876; Coverage: 100%)
  • Best match: Q14974-2 (Residues: 1-731)
Gene names: KPNB1, NTF97
Sequence domains:
Structure domains: Leucine-rich Repeat Variant
Importin subunit alpha-1 Chain: B
Molecule details ›
Chain: B
Length: 44 amino acids
Theoretical weight: 5.38 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P52292 (Residues: 11-54; Coverage: 8%)
Gene names: KPNA2, RCH1, SRP1
Structure domains: Importin-alpha, importin-beta-binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID2
Spacegroup: P21
Unit cell:
a: 64.584Å b: 97.606Å c: 83.194Å
α: 90° β: 91.13° γ: 90°
R-values:
R R work R free
0.221 0.221 0.273
Expression systems:
  • Escherichia coli
  • Not provided